Advanced Mycology — Research Brief
The Science
Technical profiles, comparison data, safety parameters, and purity methodology for XÜM (4-HO-MET) and PLÜR (5-MAPB). Clinical design. No marketing language.
Compound Profiles
XÜM
4-HO-MET
Metocin · Substituted Tryptamine
A synthetic 5-HT2A agonist. Already in its active form — no hepatic conversion required. Produces visually vivid, emotionally warm, and cognitively clarifying effects with a shorter duration and lower nausea profile.
CAS Number
77872-41-4
Formula
C₁₃H₁₈N₂O
Mol. Weight
218.30 g/mol
Solubility
Water, ethanol
PLÜR
5-MAPB
5-(2-Methylaminopropyl)benzofuran · Entactogen
A synthetic benzofuran entactogen with serotonin, dopamine, and norepinephrine releasing activity. Produces empathic, prosocial, and sensory-enhancing effects comparable to MDMA with a longer plateau, a smoother trajectory, and a lower neurotoxicity burden at equivalent empathic doses.
CAS Number
1350537-69-7
Formula
C₁₁H₁₃NO
Mol. Weight
175.23 g/mol
Solubility
Water (HCl salt)
Comparison Data
4-HO-MET vs Traditional Alternatives
Property
Traditional Alternatives
XÜM (4-HO-MET)
Active Form
Requires conversion in body
4-HO-MET (direct)
Onset
30–90 min (variable)
30–60 min (consistent)
Duration
4–8 hours
3–5 hours
Nausea / Body Load
Common
Minimal to none
Batch Purity
Varies (unverified)
≥ 99.2% (synthetic)
Dose Precision
Variable potency
Per-tab mg accuracy
COA Available
No
Yes — every batch
US Federal Schedule
Controlled in many states
Not scheduled
5-MAPB vs MDMA
Property
MDMA
PLÜR (5-MAPB)
Compound Class
Phenethylamine
Benzofuran
Primary Mechanism
SERT/DAT/NET releaser
SERT/DAT/NET releaser
Onset
30–60 min
45–90 min
Duration
3–5 hours
5–7 hours
Neurotoxicity Risk
Established at high doses
Lower at equivalent doses
Come-down Quality
Often harsh
Generally cleaner
Supply Chain Purity
Unknown (street)
≥ 99.2% verified
Adulterant Risk
High (fentanyl, cathinones)
None (COA verified)
Harm Reduction
Safety Profile
Both compounds are for healthy adults who have researched their use. The following parameters apply to all Advanced Mycology products.
Contraindications
Heart conditions, uncontrolled hypertension, personal/family history of psychosis or schizophrenia, pregnancy, nursing
Drug Interactions
SSRIs, MAOIs, lithium, tramadol, antipsychotics — all contraindicated. See a pharmacist or prescriber before use.
Age Requirement
18 years of age or older. No exceptions.
Set & Setting
Always use in a safe environment with trusted company or a sober guide. Do not operate machinery.
Start Low
First-time users should begin at the lowest recommended dose. Effects vary by individual body chemistry.
Frequency
XÜM: 2–4 week minimum between sessions. PLÜR: 4–6 week minimum. Respect serotonin recovery time.
Regulatory
Legal Status
Legal status is dynamic and varies by jurisdiction. The table below reflects our best understanding at time of writing. It is not legal advice. Verify your local laws before ordering.
Jurisdiction
XÜM (4-HO-MET)
PLÜR (5-MAPB)
United States (Federal)
Not scheduled
Not scheduled
United Kingdom
Psychoactive Substances Act
Psychoactive Substances Act
Germany
NpSG (blanket ban)
NpSG (blanket ban)
Australia
Controlled (varies by state)
Controlled (varies by state)
Canada
Controlled Drugs Act (verify)
Controlled Drugs Act (verify)
Purity Methodology
COA & Testing
Every production batch of XÜM and PLÜR is tested by an independent third-party analytical laboratory before any product ships. Testing is not optional and is not performed in-house.
Method
HPLC-UV
High-performance liquid chromatography
Threshold
≥ 99.2%
Minimum acceptable purity per batch
Frequency
Every batch
No batch ships without a passing COA
Lab
Independent
Third-party — not performed in-house
Reporting
Full quantitative
Not just pass/fail — exact percentage
Access
On request
Email us with your order number